What Is Melitide Injection? (The So-Called “Iranian Ozempic”)
If you’ve been searching for weight loss solutions, chances are you’ve come across the name Melitide injection. This Iranian-made drug is often marketed as a “miracle” weight loss option, frequently mentioned alongside global brands like Ozempic. But what’s the real story behind Melitide? Is it the same as Ozempic? How reliable is it, and should you trust it? Let’s break it all down clearly.
Melitide vs. Ozempic: What’s the Difference?
The most important point: Melitide is simply the Iranian brand name for semaglutide, the same active ingredient found in global drugs like Ozempic and Wegovy.
So, in simple terms, Melitide injection is the localized version of Ozempic, produced by Iranian pharmaceutical companies under strict regulations. Both work in the same way, using the exact same mechanism of action.

How Does Melitide Injection Work in the Body?
Slows Digestion & Prolongs Fullness
Melitide delays stomach emptying, keeping food in your stomach longer. This makes you feel full for hours, reducing unnecessary snacking and lowering daily calorie intake.
Sends “Fullness Signals” to the Brain
Semaglutide acts directly on the brain’s appetite control center, telling it: “You’re full, stop eating.” As a result, portion sizes shrink naturally without feelings of deprivation.
Regulates Blood Sugar & Insulin Smartly
For type 2 diabetics, this feature is critical. Melitide injection helps the pancreas release insulin only when blood sugar is high. This stabilizes glucose levels while reducing the risk of dangerous hypoglycemia, unlike older diabetes medications.
Also read this: What Is Trulicity Injection and How Does It Fight Obesity and Diabetes?
Who Is Melitide Injection For?
This is not a “quick fix” for losing a couple of kilos. Melitide is a prescription medication for specific patients:
- Adults with obesity: BMI ≥ 30.
- Overweight adults with health conditions: BMI ≥ 27 with conditions like type 2 diabetes, hypertension, or high cholesterol.
- Type 2 diabetes patients: Originally developed for blood sugar management, weight loss is an added benefit.

Who Should NOT Use Melitide?
Melitide injection is unsafe for some individuals:
- People with a personal or family history of medullary thyroid cancer (MTC).
- Patients with Multiple Endocrine Neoplasia type 2 (MEN 2).
- Anyone with a history of pancreatitis.
- Pregnant or breastfeeding women, or those planning pregnancy soon.
- People with severe digestive problems like gastroparesis.
- Those allergic to semaglutide.
Also read this: The most important things you should know about Maciza injection
Side Effects of Melitide Injection
Common Side Effects
- Nausea (most common, especially in the first weeks)
- Diarrhea or constipation
- Vomiting
- Reduced appetite
- Bloating and abdominal pain
Rare but Serious Side Effects
- Pancreatitis (severe abdominal pain)
- Gallbladder problems (such as gallstones)
- Kidney issues (especially due to dehydration from vomiting/diarrhea)
- Thyroid C-cell tumors (seen in animal studies → FDA “Black Box Warning”)
Dosage & How to Use Melitide Injection
Melitide comes as a pre-filled pen for easy self-injection, once a week, under the skin (abdomen, thigh, or upper arm).
Doctors start with a low dose (0.25 mg weekly) and gradually increase it every 4 weeks (0.5, 1, 1.7, up to 2.4 mg). This gradual titration helps the body adjust and minimizes gastrointestinal side effects.

Is Iranian Melitide as Good as Imported Brands?
In pharmaceuticals, generic or local versions must prove bioequivalence—meaning the same absorption, effectiveness, and quality as the original drug.
So if you buy Melitide injection from a licensed pharmacy with proper cold-chain storage, you can trust that it works the same as Ozempic.
⚠️ The critical factor is storage in refrigeration. Always ensure the product is properly stored and transported.
Quick FAQs About Melitide
On average, clinical studies show 10–17% of body weight reduction within a year, depending on diet and activity.
Yes. Obesity is a chronic condition, and stopping the drug without lifestyle changes often leads to gradual weight regain.
For type 2 diabetes, often yes. For obesity treatment alone, usually no.
No. Melitide is prescribed for obesity or overweight with health risks—not cosmetic weight loss.
Final Word
Melitide injection is a highly effective treatment option in Iran for both obesity and type 2 diabetes. Containing the same active ingredient as Ozempic, it helps control appetite, regulate blood sugar, and support sustainable weight loss.
But remember: it’s not a magic wand. For best and lasting results, use it under medical supervision alongside a healthier lifestyle, balanced diet, and regular exercise.